Gay Marriage Should Be Legal Essay - 1666 Words

On June 26, 2015, the US Supreme Court ruled that the US Constitution guarantees the right for same-sex couples to marry in all 50 US states. Associate Justice Anthony Kennedy stated in the majority opinion: The court now holds that same-sex couples may exercise the fundamental right to marry. No longer may this liberty be denied to them. Marriage between same-sex couples continues to be a heated issue of debate in society today. Denying gay marriage affects gay and lesbian couples and lets people think that is acceptable to discriminate against them. Even though same-sex couples are not natural, people should be able to get married to whomever they want no matter the gender because you can’t invariably choose who you fall in love with†¦show more content†¦Even though gay couples cannot procreate they will be taking millions of children out of foster homes giving them a safe and loving home. Gay parents tend to be more motivated and committed to their child because if they have children, you know they truly want to take on that responsibility because they chose to be parents. The lack of support of marriage rights denies children the same protections that the â€Å"traditional† family has and negatively affects them by saying that their parents are second-class citizens who are not treated equal in society. The majorities of teenagers today are being bullied due to the fact of their sexual orientation and is resulting in many children committing suicide because of it. Out of all the students in the U.S., 75 percent have no state laws to protect them from harassment and discrimination in school. Teenagers that are being bullied just want to be accepted for who they are and when gay marriage is legal nationwide they will feel that acceptance and respect. Discrimination could cause psychological distress, social conflict and ill-health Children raised in same-sex households seem to have better self-esteems because their parents allow them to explore and be themselves. I believe that if we work together and stop the hate, we could saveShow MoreRelatedGay Marriage Should Be Legal1205 Words   |  5 PagesHoward Sociology 1301-93431 Gay Marriage Getting married is something that most people do when they find love, which it is an important event in their life. The GLBT (gay, lesbian, bisexual and transgender) community now get the legal right of same-sex marriage, which they have fought for throughout the years; on the other hand, some opponents of same-sex marriage have called for a constitutional change towards it. Although there were some countries that allowed gay marriage before the United StatesRead MoreGay Marriage Should Be Legal1159 Words   |  5 PagesAmendment, which puts a ban on gay marriage. This amendment entitles to equal rights to the gay community, ending toleration of discrimination in jobs, rights protecting gays from hate crimes,rights allowing advancement in government. However, the concept of gay marriage is still not considered a right the American people should extend to homosexuals. II. The vast majority of opponents believe marriage should be between one woman and one man, meaning marriage should be between members of the oppositeRead MoreGay Marriage Should Be Legal1574 Words   |  7 Pagesequal rights. Gays and lesbians are consistently denied rights that are typically taken for granted by the average American. Specifically, gay and lesbian couples are denied the right to marry even if they are outstanding citizens. They are held at an unfair disadvantage solely because of their sexual orientation. This discrimination must stop, because gay and lesbian couples are law-abiding citizens too, who should be afforded the same rights as heterosexual couples. Marriage is about love andRead MoreGay Marriage Should Be Legal1564 Words   |  7 PagesWhat is marriage? Recently, people argue with respect to the definition of marriage. What happened to marriage? To get married is a very important event for almost everyone. Especially for women, marriage and giv ing a birth could be the two biggest events of their lives. Many people believe that getting married to the one whom he or she loves is natural. However, what do you think if you cannot get married to him or her because it is socially unacceptable? 100 years ago different colored peopleRead MoreShould Gay Marriage Be Legal?778 Words   |  3 PagesShould Gay Marriage Be Legal? â€Å"†¦I now pronounce you husband and wife†¦Ã¢â‚¬  One would normally hear this when attending a wedding. In tradition marriage has been between one male and one female who love each other. But how would one feel if they heard â€Å"I now pronounce you groom and groom† or how about â€Å"†¦bride and bride...†? In the last 50 years the number of same-sex couples has increased. The on-going argument between the government and the people is â€Å"Should gay marriage be legal?† Although some sayRead MoreGay Marriage Should Be Legal1126 Words   |  5 PagesJune 26, 2015 for gay marriage to be legal in all fifty states, thirty seven out of the fifty and Washington D.C already legalized gay marriage. Many support gay marriage and many do not, with widespread values and reasons for and against it. Due to religion and rights people across the nation have differing views and opinions of it.In a five to four vote in the Supreme Court gay marriage becam e legalized in all fifty states. Shortly after that a few marriage officiators and marriage licenses peopleRead MoreGay Marriage Should Be Legal1179 Words   |  5 PagesGAY MARRIAGES Some states such as Iowa legalized gay marriage through the action of judicial interpretation based on the state’s constitutional stipulations while other states such as Vermont legalized gay marriage through legislation initiatives. These cases demonstrate the government is the sole body that can dictate the validity of whatever is to be regarded as a marriage, and in this case gay marriage. The power to validate marriage is still observed among the private citizens, religious institutionsRead MoreThe Gay Marriage Should Be Legal947 Words   |  4 PagesDefending Gay Marriage During the last few years, homosexuality has become an important issue for debate. Moreover, homosexuals have taken their case further by claiming their right to marry. Same-sex marriage, usually known as â€Å"gay marriage†, is the marriage between two people from the same biological sex (Doskow1). Since 2000, eleven countries have approved the legalization of gay marriage worldwide: Netherlands, Belgium, Spain, Canada, South Africa, Norway, Sweden, Portugal, Iceland, ArgentinaRead MoreGay Marriage Should Be Legal1480 Words   |  6 PagesNew World Dictionary defines the word married as being husband and wife, yet there are millions of gay activists who are fighting for a new meaning. They believe marriage is more than a piece of paper and a set of rings. The hope is that marriage could be defined as a â€Å"public recognition of a private commitment† or â€Å"emotional, financial, and psychological bond† between two people (Sullivan 53). Gay activists belie ve that taking away the ability to have a publicly recognized relationship or an acceptedRead MoreGay Marriage Should Be Legal1351 Words   |  6 Pageshappened for United States, gay marriage became legal in all 50 states. In most states it already was but the remaining 13 became legal this year. There are many concerns regarding gay marriage, and the effects of them involve many legislative, cultural, religious and family issues. Gay marriage is controversial because a lot of people do not approve of it, they think it is immoral, unnatural, and not what the traditional concept of â€Å"marriage† really means. Opponents of gay marriage say it is only meant

Beowulf The Oldest Surviving English Poem - 2174 Words

Kyana Campbell June 16, 2015 World Literature Professor Jacobs Beowulf The epic poem Beowulf is known to be the oldest surviving English poem. It is written Old English or some call it Anglo-Saxon, which is the basis for the language we speak today. Many epics were not originally written down by their authors. Instead, they were memorized and retold or sung by wandering entertainers. Beowulf was written somewhere between the 8th and 11th century, the exact date is unknown and the author of this poem also remains unknown. With Beowulf being the oldest poem in the English language, everything written after it has to come from Beowulf in some way. With that being said, there is a lot to be learned from this poem. In particular, the story of Beowulf covers common themes that we still see in English literature today. Specifically, one major theme that we often see in this poem is Good vs. Evil. Throughout Beowulf there are many battles that Beowulf himself has to take on. This poem gives us a better understanding of the meaning and significance of the theme Good vs. Evil. Beowulf was someone that people viewed to be a superhero. He was a man who went and rescued anyone in need of help. For example, Beowulf sailed to another country to fight a demon and protect a king and his people from continuously being attacked by this monster. Beowulf had no problem risking his own life especially when it was to protect others. This demon that Beowulf was going to face could destroyShow MoreRelatedThe Journies of Beowulf and Sir Gawain and the Green Knight Essay803 Words   |  4 PagesBeowulf vs. Sir Gawain and the Green Knight In the worlds of Beowulf and Sir Gawain and the Green Knight, the journeys of two heroes, Beowulf and Sir Gawain, are depicted through the form of poems. The two stories have become two of the most important works of literature in the English history. In the two poems, both Beowulf and Sir Gawain face great challenges in their journeys as heroes. Beowulf embarks on a quest to defeat Grendel and his mother while Sir Gawain faces many difficulties on hisRead MoreAnalysis Of The Poem Beowulf 851 Words   |  4 Pagesliterary analysis of Beowulf, the oldest epic poem that has survived in English literature. It is also widely known as the earliest surviving piece of literatures in vernacular European Literature. The language of this poem is Old English, spoken by Saxon people. This poem depicts a traditional story that is a part of oral Germanic tradition. As per experts, this is work of a single poet and was composed in then England. It has been determined by the scholars that this po em was written between 8thRead MoreThe Epic Of Beowulf By William Shakespeare1176 Words   |  5 Pagesbeen nearly fifteen movies that were made after â€Å"Beowulf†. It may be due to the fact that â€Å"Beowulf† is one of the most famous epic poems in the English Literature history. It is also the oldest surviving epic poem to date. â€Å"Beowulf† was written in 10000 AD in Old English by an author who remains unknown. In â€Å"Beowulf†, there are many important literary elements that help empathize the main motif of the poem. The motif of this poem is courage. Beowulf is about courage and it is shown through the charactersRead MoreBeowulf Is The Oldest Recorded Poem1328 Words   |  6 PagesThe epic poem, Beowulf, is the oldest recorded poem in English and at 3200 lines long, comprises roughly ten percent of the surviving poetry in Old English. Although written in this language, Beowulf focuses on the feats of the poem’s namesake Beowulf, a Ge atish prince, and the invading Germanic tribes in Denmark. Understood early on in the poem, these tribes have a lengthy and powerful warrior culture; a culture heavily influenced by heroic virtues, blood vengeance, and paganism. Along with theseRead MoreTheme Of Heroism In Beowulf1139 Words   |  5 Pagesâ€Å"Beowulf† is the oldest surviving poem in Old English Literature. It is an epic poem, which is a narrative poem typically revolving around heroism. The poem emphasizes repetitively on how Beowulf is a hero. He saves countless people from countless monsters, three of which are the main antagonists in the poem – a demon, the demon’s mother, and a dragon. But is saving innocent lives the only factor to justify and determine a person’s heroism? Throughout the story of Beowulf, the author makes appealsRead MoreEssay On Translation Of The Movie Beowulf953 Words   |  4 PagesBeowulf is the oldest surviving epic poem in Old English literature. It is a t ale as old as time, passed down through stories around the campfire, told through the ancient lips of our ancestors. There were many translations recorded as soon as writing was developed, but one was more accurate and popular than the rest. In the year 2007, the movie Beowulf was produced, and it combined many translations of the poem. There were major similarities and differences between the most accurate translationRead MoreBeowulf : The Ideal Anglo Saxon Warrior871 Words   |  4 PagesAnglo-Saxon Warrior Throughout the epic of Beowulf, the differences between the hero of Beowulf and the villain of Grendel are made clear. Taking place during the fifth century, Beowulf is commonly known as the oldest surviving epic poem of Old English. It is also considered one of the most important works of Anglo-Saxon literature. With a different age and time period comes different values. Many of the traits greatly admired during the time of Beowulf may now have much less emphasis placed on themRead MoreEssay on Good vs Evil in Beowulf1568 Words   |  7 PagesIn Beowulf, the clash between good and evil is the poems main and most significant focal point. Although the epic poem Beowulf utilizes many characteristics of Christian themes, the violence in the poem relates to paganism. By exploring the characteristics of â€Å"good vs. evil† such as Cain, Grendel and Beowulf, this paper will explore the elements of Beowulf in such a light. The Anglo-Saxon poem, Beowulf, was originally told orally then later was written down anonymously in the Old English languageRead MoreHarry Potter And The Sorcerer s Stone969 Words   |  4 Pagesgreat risk, while performing acts of courage. This definition can be related in the epic poem, Beowulf, and the novel, Harry Potter and the Sorcerer s Stone. In each story, both leading characters are born destined to defeat the most evil creature in their world. Beowulf is the oldest surviving epic poem in the world. â€Å"Beowulf† was written in 1000 AD, in Old English form. In this poem the main character, Beowulf, challenges an evil monster, Grendel and a dragon, to a battle to save Denmark. 1,300Read MoreBeowulf: The Canonization of Anglo-Saxon Literature into Modern Popular Culture769 Words   |  4 Pages The cover of the November, 1975 comic book Beowulf: Dragon Slayer features a red-haired, horn-helmeted Beowulf swinging a large broadsword at a purple-caped villain also bearing two razor-sharp swords. As Beowulf rears up on his steed, a bikini clad woman, cloth slightly aside to reveal the shadow of a buttock is drawn falling, face filled with terror. In the background, a rising full moon and silhouetted gothic castle keenly set an atmosphere of dread and foreboding. Above the emboldened

Streets in Today’s Age Free Essays

string(196) " Datta describes Barrabazar as, â€Å"†¦ the country was diverse and included stores, godowns, residential edifices and bustis, though commercialisation had lent the whole ward a typical character\." Dissertation Subject: Streets in Today’s Age Introduction: On a wider range, a metropolis is the base of invention, a platform for advancement of world, the stopper of power and hub for all societal, cultural and economic public assistance. Broadly, the metropolis provides solutions to show and unanticipated jobs, because things and phenomena take topographic point in the metropolis – a conglobation of clerisy. The metropolis grows and develops when it is in theodolite ; better the velocity, faster is its rate of advancement. We will write a custom essay sample on Streets in Today’s Age or any similar topic only for you Order Now And so is the construct of roads, where the fastest moving options are idealized. A street, though provides traffic motion, is a modest interlingual rendition of a route. Defined by borders of edifices, their fenestrations, adorned with tree lines, public activity is the trademark of a street. A Street marks the theodolite of the metropolis, yet, with the utmost solution happening step of edifice roads, our metropoliss have seen an upward tendency of change overing streets into roads. The thought of streets, in Indian scenario, can non be imagined without the informal activities of economic sector – the shoemaker, the seller, the tea stall, etc. these form the service countries every bit good as absolutely act as a back uping function to an synergistic life in the society. Now, because of the tendency of formalising every sector of economic system and transition of streets into roads, we lose the most of import usher to our societal life. On the contrary, because of the gait of our life, the ‘leftover pieces of streets’ on the present twenty-four hours roads simply warrant their character. For it is imperative that velocity governs the growing of the metropolis and the day-to-day life of its dwellers. Therefore, the really ‘solutions’ to the jobs of the metropolis, are disguised ‘problems’ of the turning metropolis. The thought of this thesis is to place the existent practically feasible stretches of street which can be or hold a range of set uping back into streetscapes. I would look into such stretches of streets and critically analyse its features employed in and around the country ; of how are its border conditions, how the street permeates into activities related specifically of the country. Therefore, while keeping the kernel of streets, this thesis aims to reevaluate the function of streets in the urban cloth of the metropolis activities in today’s visible radiation. Purposes: To understand the function of streets in today’s context. To measure up streets as practical entity to last the demands of the hereafter. To understand the practical deductions and Scopess of streets revival Aim: To research the multiple roles a street dramas in today’s urban context, stressing the usage of streets. To place the indispensable stretches of complete street and its kernel in the part around it. To understand the features of these specimen stretches. To analyse their border conditions, their Scopess of permeableness, degree of integrating with the societal facets of its users, etc. LITERATURE REVIEW: Patrick Geddes and the Metropolis, Partho Dutta The really ‘modern’ construct of urban planning became a outstanding country of treatment in the planning societies and diaries throughout the western universe, when the determination to switch the capital of colonial India from Calcutta to Delhi was taken in 1911. Other urban centres in colonial India of some distinguished bequests excessively came under the scanner of urban contrivers and the discourse of modern planning permeated in many Indian towns and metropoliss. Partho Dutta presents this paper in the 20Thursdaycentury puting to look at the ongoing contextual alterations in the colonial universe with regard to the metropolis of Calcutta. Colonial metropoliss were looked at with a common yarn of concerns and attitudes laid down by the British Empire – that was of the bonus to migration into metropoliss and the jobs of overcrowding and insanitation due to the rapid growing of mill based industries. This led to blight in 1896 and the primary concern of the colonial authorities was to safeguard the countries with important European populations. Thus modern planning in India had its root in the 19th century pandemics ( Gupta N, 1981 ) . Improvement Trusts were set up and the town planning motion gathered a impulse. Though, altering metropoliss meant altering people and therefore in bend meant altering society itself ( Topalov C, 1990 ) . After the efforts of the province to sanitise the family clashed with the traditional Indian impressions of pureness and pollution ( Dutta P, 2012 ) , the colonial town contrivers took an easy manner out by automatically implementing the Haussmannian theoretical account – of cutting wide wrappings of roads across the life colonies for efficient traffic circulation. Here in, Datta introduces Patrick Geddes as a contriver who is ‘culturally informed’ ( Goodfriend D, 1979 ) . Geddes believed that the capitalist modernisation has brought sea-changes, but had been unable to obliterate critical cultural symbols ( Chakraborthy S ) . He argued that the programs of the hereafter could merely be drawn on a thorough disentangling survey of the societal cast of the community. He put forth the ‘the diagnostic or civic survey’ procedure of recovery to ‘feel’ the organic signifier of the metropolis. A complimentary ‘conservative surgery’ to his civic study provided merely the needful intercessions, therefore bettering maximally by minimum devastation. He quotes, Tyrwhitt J ( 1947 ) : â€Å"†¦the method of Conservative Surgery.. , first it shows that the new streets prove non to be truly required since, by merely enlarging the bing lanes, ample communications already exist ; secondly that, with the add-on of some vacant secret plans and the remotion of a few of the most bedraggled and unsanitary houses, these lanes can be greatly improved and every house brought within the range of fresh air every bit good as of stuff sanitation – a point on which the more pretentious method invariably fails, as is apparent on every plan.† With the rules of Geddes in topographic point, Partho Dutta trains his gun on the Burrabazar, cardinal Calcutta’s most engorged and of import concern territory ; Geddes’ foremost proper to-be committee in colonial city. Datta describes Barrabazar as, â€Å"†¦ the country was diverse and included stores, godowns, residential edifices and bustis, though commercialisation had lent the whole ward a typical character. Overbuilt with narrow streets, which made it cryptic and impenetrable to authorities bureaus, its insanitation worried decision makers because of its close propinquity to the centre of authorities ( Writers Building ) . †¦ By reconstructing order in this ward, the authorities contrivers wanted to make a buffer between the Indian vicinities to the North and British 1s in the South. †¦ ( by the ) proposed Central Railway Station.† The CIT ( Calcutta Improvement Trust ) indicated that the ‘allocation’ of streets, cloacas and railroad lines seemed the lone manner to order the metropolis ( Boyer C, 1994 ) . Thus a destruction temper was set in the heads of the functionaries. When all other European disciplinary proficient functionaries had called in for a destruction, Patrick Geddes was called in for his study, as a town contriver, on the Barrabazar destruction thrust. As Ram Guha ( 2005 ) points out, Geddes confronted two major strains in modern planning at odds with each other. â€Å"†¦ the close association of concern demands to urban planning: the proliferation of capital had ever meant to restructuring of spaces†¦ and the other being the curse of modern be aftering how to rehouse the displaced working categories without arousing category conflict.† His study recommended three parametric quantities ; foremost, the debut of new street should aline east- West axis, the natural motion of goods and traffic flow. Second, the north eastern portion of Barrabazar was to retain its residential character and to develop the west country into modern concern Centre. Third, the minimum destruction of unsanitary belongings to happen, would be rebuild maintaining traditional urban signifiers in head to maintain the character of the territory intact. The CIT programs were motorized conveyance based, but harmonizing to Geddes, betterment in prosaic circulation was the current demand within Barrabazar, since grounds of mass circulation by pes, human portage and manus driven carts was excessively apparent. He was really vocal on the saving and extension of lanes, as Dutta quotes Geddes ( 1919 ) : â€Å"A lane after all is a paving without a route beside it, and some people value its soundlessness ; while its narrow breadth and shadiness gives coolness also.† His program showed hierarchy of roads – lanes for walkers, streets for assorted traffic, and roads for intra-city communicating. This would avoid choke offing up of individual avenues with motors, worlds, animate beings, thereby haltering mobility. His separation of traffic maps enabled faster velocity for vehicles and mobility for commercialism, still continuing the bing channels of communicating. Among some other natural intercessions discussed in his paper, Partho Dutta high spots on Geddes’ strategy for little unfastened infinites between houses – where he suggested planting of few trees to keep the holiness of these little countries and promote people to maintain them clean ( Geddes P, 1919 ) . His thought to do survive an unfastened infinite was to incorporate it with the community instead than go forthing it as a healthful ‘void† , as Parkss and gardens. Towards the terminal, Dutta puts frontward critics to Geddes’ work yet how his attempts could non stand tall to the might of the colonial powers meant for suppressing the province. Even though the paper is a record of Patrick Geddes’ work on Barra Bazar, Partho Dutta had to the full been successful in showing the Geddesian attack to street forms and public kingdom, by preservation of traditional ethos in town planning. His thought of non giving in to meaningless modernisation fad and seeking the optimum from the remainder inspires a manner towards look intoing the inquiries in my thesis. Autochthonal Modernities, Negotiating Architecture and Urbanism, Jyoti Hosagrahar A book written on the urban history of Delhi,Autochthonal Modernitiesis ambitious in its attempt to show the important alterations in the societal and physical surroundings of Delhi, in a period of a century between 1857 and 1947. Harmonizing to Jyoti Hosagrahar, these alterations though â€Å"modern† in their attack, were toned to autochthonal prescriptions, thereby coining the term, â€Å"Indigenous Modernities† ( Appadurai A, 1996 ) . The modernisation in Delhi was non an infliction from outside, but a homegrown endeavor germinating from within bing societal cloth. The modernisation of Delhi is seen in a intercrossed signifier, non ideal unidirectional type as envisaged by the planetary infliction of modernness. Infrastructure development, usage of new engineerings, debut of fresh public establishments, and growing of new lodging typologies are the illustrations of these intercrossed signifiers. Every alteration in the societal imposts and physical infinites was chal lenged, bargained, abandoned, and adjusted. The terminal consequence of which was non a picket or a lacking version of European modernism, but something which imbibed traditional and modern, old and new ; coexistence adopted anxiously ( Gupta N, 1981 ) . Hosagrahar establishes the metropolis of Delhi as a cultural landscape and sets the temper of the reader in the clip frame which rendered the glances of modernness in it. In five chapters she traces the decomposition of the domestic infinites ofhavelis ;the backdown of the community from the public kingdom ; the dislocation of traditional wellness and healthful systems ; denationalization ; and the commodification of community belongings. A brawny monetary value of modernisation was to be paid as it combined urban reforms with profit-seeking motivations. The many imposed societal alterations were cancerous and had the possible to destruct the societal cloth. However, the colonised dwellers proved resilient and appropriated modernness in ways they saw tantrum, guaranting their endurance and heightening their life chances. Delhi survived the going of feudal system, the birth of patriotism, and the attainment of independency, all in less than a century. The book highlights the monetary value that the metropolis paid and its dirty additions in private and public domains. In the wake of the Mutiny/First War of Independence ( 1857 ) ,havelis, abodes of landowning aristocracy, suffered from disregard and were converted into warehouses and smaller residential units ( Verma P and Shankar S, 1992 ) . These big houses had been the pillar of vicinities, because the residents supported craftsmans and their trades. At the same clip, the lifting entrepreneurial categories sought to populate in intercrossed versions of courtyard lodging and European-style cottages. Although the courtyards shrank and drawn-out households fragmented, older life styles did non vanish wholly. Attempts to bring forth public infinites as apublic goodwere contested passionately, accustomed as the occupants were to utilizing available land for their ain intents. Enforcement of bylaws and other ordinances met with considerable opposition since affairs refering belongings rights and territorial invasions had antecedently been resolved within the community or arbitrated by the seniors. New urban infinites generated by the edifice of establishments such as the town hall became the locales for nationalist presentations, so a sort of civic kingdom, independent of spiritual or royal associations, did emerge, even though it had a conflict-ridden generation. New medical systems of cognition and the pattern of their engineerings produced infinites and built signifiers — infirmaries and dispensaries — that did non wholly displace the stores ofhakimsandvaids, practicians ofunaniandayurvedicsystems of traditional medical specialty. Similarly municipal services including pipe d-water supply, sewerage systems, and trash aggregation did non ensue in the ostracism of sweepers. Hosagrahar draws upon municipal archives and her ain interviews with Delhi occupants to compose an urban narration that is handsomely illustrated with historic maps and exposure. The earlier chapters onhavelis, streets, and geographicss of wellness brand for more interesting reading than the last two chapters on land development and new lodging undertakings meant to make a â€Å" modern † citizen. In the narrative Hosagrahar sketches out for us, neither the coloniser nor the colonised appears to move out of baronial motivations, although the capable population deserves our understanding in their efforts to do sense of rapid societal alterations and adapt to them. While there was no straight-out rejection of modernness ( except possibly the last despairing gesture of rebellion in 1857 ) , there was considerable opposition to bumbling autocratic steps every bit good as reformer dockets. Private involvements, more frequently than non, triumphed over public good. In the 21st century, a new embodiment of colonialism, globalisation, is one time once more altering the urban landscape of Delhi. Just as sectors such as Civil Lines, Cantonment, and New Delhi consumed a far greater figure of resources and were dependent upon old Delhi for services, so make the new satellite metropoliss of Gurgaon and Noida depend upon older subdivisions of the metropolis. And merely as New Delhi ‘s landscape was â€Å" modern † in its definition, resting upon its differences from Shahjahanbad/old Delhi, so make these new developments aspire to a feel and image that isplanetary, derived from Western paradigms ( King A, 2004 ) .Dualities abound in post-independence Delhi. Municipal services in most subdivisions remain unequal, chunky settlements proliferate, there is an acute H2O deficit, and most citizens do non hold entree to healthful systems. This landscape of poverty is juxtaposed with a landscape of luxury in shopping promenades, skyscrapers, and hu ge verdure. With hindsight, it is alluring to categorise the late nineteenth- and early twentieth-century attempts as a failed or uncomplete undertaking of modernness, destined to prevail in its mutant signifier into the following century ( Sinha A, 2007 ) . Possibly the flight of modernness would hold been different had its undertakings been implemented with greater sensitiveness to cultural codifications and customary patterns ; we should be after for the hereafter consequently. REFERENCE List: Gupta Narayani, 1981, Delhi Between Two Empires, 1803-1931: Society Government and Urban Growth, Oxford University Press, Delhi. Topalov Christian, August, 1990,‘From the â€Å"social question† to â€Å"urban problems† : Reformers and the working categories at the bend of 20th century’ ,International Social Science Journal, No.125. Dutta Partho, 2012, Patrick Geddes and the Metropolis, Nehru Memorial Museum and Library, New Delhi, pg. 3 Goodfriend Doughlas E, winter, 1979, ‘Nagar Yoga: The Culturally Informed Town Planning of Patrick Geddes in India 1914- 24’ ,Human Organization38, No. 4. Insight by late Prof. Satyesh Chakraborthy, Calcutta Tyrwhitt Jacqueline, 1947, Ed. Patrick Geddes in India, Lund Humphries, London, pg. 41 Guha Ram,2001, Patrick Geddes and Ecological Town Planning in India, a talk at the Urban Design Research Institute, Bombay, October 5, 2001. Boyer M. Christian, 1994,Dreaming the Rational City: The Myth of American City Planning, Cambridge, Mass. , MIT Press, 1983, pg 288 Geddes Patrick, Barra Bazar Improvement, A Report ( Calcutta: Corporation Press, 1919 ) pg 12 Geddes Patrick, Barra Bazar Improvement, A Report ( Calcutta: Corporation Press, 1919 ) pg.32 Hosagrahar Jyoti, 2005, Autochthonal Modernities: Negotiating Architecture and Urbanism, Routledge, London. Appadurai Arjun, 1996,Modernity at Large: Cultural Dimensions of Globalization, Minneapolis, MN: University of Minnesota Press, pg3 Gupta Narayani, 1981, Delhi Between Two Empires, 1803-1931: Society Government and Urban Growth, Oxford University Press, Delhi. Verma Pawan and Shankar Sandeep, 1992,Sign of the zodiacs at Dusk: the Havelis of Old Delhi; Spantech Publications, New Delhi. Sinha Amita, Report on Hosagrahar’s Delhi Identity, February 2007 King Anthony, 2004,Spaces of Global Culture: Architecture, Urbanism, Identity, Routledge, New York. How to cite Streets in Today’s Age, Essay examples

Review The Importance of Being Earnest Essay Example For Students

Review The Importance of Being Earnest Essay In The Importance of Being Earnest we’ll meet two Ernest’s who will truly teach you the vital importance of being Ernest. Or was it no Ernest’s? Maybe it was one Ernest. The whole situation with names in this fantastic film can be quite confusing at times, but for the most part it helps to keep the laughs coming in bunches. Throughout this gut wrenchingly hilarious film two men will learn the vital importance of being Ernest. Perhaps if you give it watch you might as well. To open up the movie, you see one of the leading male roles, Algernon a. . a. Ernest, running from the bill collectors late at night. He is somewhat of a laid back spirit. While Algernon is part of the upper class and is very wealthy he is bored with the half of the lifestyle which does not include any of the following; parties, women, and booze. The other leading role male character is Jack also a. k. a. Ernest. He is a little bit more uptight than Algernon and takes much more responsibility, but is also Algernon’s best friend, only Algernon knows him as Ernest. Jack is in love with Algernon’s cousin Gwendolen. Algernon is in love with Jack’s ward, Cecily. As you are probably thinking right now, this gets interesting. Cecily Cardew, Jack Worthing’s ward, pretty, 18, and the future Mrs. Algernon Moncrieff, but not if Jack has anything to say about it. Cecily is a young very pretty, very smart girl, in love with Jack’s â€Å"younger brother† Ernest and has had a 3 month engagement with him that she only knows about. Very smart, pretty, and extra crazy, what’s not to love? She also happens to be soon to be sister to Gwendolen Bracknell, Jack’s love interest, cousin of Algernon. Not much to say about her, but rich, pretty, and completely controlled by her slightly insane mother, Lady Bracknell. Gwendolen is in love with Jack, but as Ernest and would love to marry him, but Lady Bracknell does not approve, nope, not one bit. As previously mentioned, Lady Bracknell is a little bit crazy, but also stuck up and snooty, along with some other choice adjectives. She wishes to find Gwendolen a husband at the young women debuted and absolutely flips out when she finds out. TIOBE showcases a brilliant plot that is flawlessly scripted in a way that has you literally rolling on the floor laughing the whole time. It’s all about two best friends, Algernon and Jack, who go bunburying as someone’s fake little brother(Ernest Worthing, false younger brother of Jack) in order to win the love of the women they love. Each girl with non-approving guardians. It just may have worked if only they both didn’t propose to the girls as Ernest. Even though their lies eventually unfolded everything somehow seemed to work itself out. Attributing to the happy ending are a crazy in-law and a long lost family friend, to go with some more lies and lots more truths. A lot of times movies with great plots and great potential are ruined by the acting of poorly selected actors. TIOBE just so happens not to be one of those cases, thankfully. The actors in the film showcase excellent chemistry and comedic timing throughout the entire 97 minutes run time. They brilliantly displayed their abilities to deliver laughs not only in the form of hilarious zingers, but with great expression. Something else to be mentioned is their impeccable delivery of each line feeding you as much joy and laughter as possible. Overall for the acting in this film, all I can say is that it was fantastically hilarious. .uf18213be6ed5bc6b0fde9e3f54dea184 , .uf18213be6ed5bc6b0fde9e3f54dea184 .postImageUrl , .uf18213be6ed5bc6b0fde9e3f54dea184 .centered-text-area { min-height: 80px; position: relative; } .uf18213be6ed5bc6b0fde9e3f54dea184 , .uf18213be6ed5bc6b0fde9e3f54dea184:hover , .uf18213be6ed5bc6b0fde9e3f54dea184:visited , .uf18213be6ed5bc6b0fde9e3f54dea184:active { border:0!important; } .uf18213be6ed5bc6b0fde9e3f54dea184 .clearfix:after { content: ""; display: table; clear: both; } .uf18213be6ed5bc6b0fde9e3f54dea184 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .uf18213be6ed5bc6b0fde9e3f54dea184:active , .uf18213be6ed5bc6b0fde9e3f54dea184:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .uf18213be6ed5bc6b0fde9e3f54dea184 .centered-text-area { width: 100%; position: relative ; } .uf18213be6ed5bc6b0fde9e3f54dea184 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .uf18213be6ed5bc6b0fde9e3f54dea184 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .uf18213be6ed5bc6b0fde9e3f54dea184 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .uf18213be6ed5bc6b0fde9e3f54dea184:hover .ctaButton { background-color: #34495E!important; } .uf18213be6ed5bc6b0fde9e3f54dea184 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .uf18213be6ed5bc6b0fde9e3f54dea184 .uf18213be6ed5bc6b0fde9e3f54dea184-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .uf18213be6ed5bc6b0fde9e3f54dea184:after { content: ""; display: block; clear: both; } READ: The Fast and The Furious EssayOverall, I found TIOBE to be a fantastically well written film, adapted from a fantastically well written play. From the portrayal of the characters, to the fantastic plot, and the spot on acting I felt that this film was right on the money with where it stood. The only thing that could possibly beat it I feel would be a remake staring Zac Effron and Jennifer Lawrence and I don’t see that happening any time soon. So, if you’re in the mood for a comedy that will have you laughing for an hour and a half The Importance of Being Ernest is it.

Tourism and Sustainability Whale

Characteristics for Development of Whale-Watching Industries On the social front, it is evident that although the community in the Vava’u area comprises of only 16,000 people, it has been on the forefront in whale conservation efforts and demonstrates a friendly nature to tourists. Additionally, the community has been effective in using promotional material involving the humpback whales to put Tonga on the world map.Advertising We will write a custom assessment sample on Tourism and Sustainability: Whale-Watching Industries specifically for you for only $16.05 $11/page Learn More On the economic front, it is clear that tourism is the economic mainstay of the Vava’u area due to the fragile nature of other economic activities mainly in the manufacturing, agricultural, forestry and service sectors, hence making the area a fertile breeding ground for the development of modern whale-watching industries. Concerning the natural environment, the Va va’u Island group in the Kingdom of Tonga is not only located in a tropical climate with warm, sheltered waters but also prides itself for hosting one of the whale species most popular for tourism. The high-quality marine environments in the area ensure the availability of humpback whales, which often visit the area for mating, birthing, and raising young calves. Non-Economic Impacts of Whales and Whale-Watching As demonstrated by the author of the article, tourism activities occasion both economic and non-economic impacts in the destination area or country. In the context of the Island of Tonga, whales and whale-watching activities are likely to occasion difficulties in hosting large numbers of tourists, environmental pollution and degradation, conflict between operators, resentment in the local community fuelled by increasingly large numbers of tourists, and internalization of vices such as prostitution and gambling among the local people. Other non-economic impacts of whal es and whale-watching activities likely to affect the Island of Tonga include inflationary pressure in the local economy, loss of local control on how local resources are managed and distributed, as well as environmental degradation due to the establishment of numerous whale-watching businesses in the area. However, a positive non-economic impact for the Island concerns the change of attitudes and value systems among the local community, especially in terms of valuing and conserving the humpback whales as a critical resource for social and economic development of the Kingdom. Factors influencing Potential Future Growth of Whale Watching Some of the factors that will guarantee the future growth of whale-watching industry in Vava’u Island group, as demonstrated by the author, include (1) developing adequate transportation, accommodation, and other elements of the tourism infrastructure, (2) attaining long-term political stability not only in the Island of Tonga but also in Sout h Pacific region, (3) establishing convenient and reliable airline connections to boost tourists’ arrivals, (4) dealing with unsustainable whale hunting practices, (4) establishing proper management practices for whale-watching activities, (5) dealing with negative social, economic and environmental impacts associated with tourism, (6) maintaining a stringent code of practice for whale-watching operators to minimise negative impacts associated with competition, and (7) establishing adequate conservation initiatives for the humpback whales to maintain their health and value.Advertising Looking for assessment on communications media? Let's see if we can help you! Get your first paper with 15% OFF Learn More It is important to note that several factors discussed in the article, including degradation of the natural environment, non-involvement of the local community and proliferation of unsustainable hunting practices may actually hamper the growth of the whale-wat ching industry in the future if immediate corrective measures are not taken. Overall, it can be suggested that the sustainability efforts undertaken to guarantee the expansion of the whale-watching industry in the Island of Tonga are bearing fruits. This assessment on Tourism and Sustainability: Whale-Watching Industries was written and submitted by user Nickolas U. to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Major General J.E.B. Stuart in the Civil War

Major General J.E.B. Stuart in the Civil War Major General J.E.B. Stuart was a famed Confederate cavalry commander during the Civil War who served with General Robert E. Lees Army of Northern Virginia. A Virginia native, he graduated from West Point and aided in quelling the Bleeding Kansas crisis. With the start of the Civil War, Stuart quickly distinguished himself and proved an able and daring commander. Leading the Army of Northern Virginias cavalry, he took part in all of its major campaigns. Stuart was mortally wounded in May 1864 at the Battle of Yellow Tavern and later died in Richmond, VA. Early Life Born February 6, 1833 at Laurel Hill Farm in Patrick County, VA, James Ewell Brown Stuart was the son of War of 1812 veteran Archibald Stuart and his wife Elizabeth. His great-grandfather, Major Alexander Stuart, commanded a regiment at the Battle of Guilford Court House during the American Revolution. When Stuart was four, his father was elected to Congress representing Virginias 7th District. Educated at home until age twelve, Stuart was then sent to Wytheville, VA to be tutored before entering Emory Henry College in 1848. That same year, he attempted to enlist in the US Army but was turned away due to his young age. In 1850, Stuart succeeded in obtaining an appointment to West Point from Representative Thomas Hamlet Averett. West Point A competent student, Stuart proved popular with his classmates and excelled at cavalry tactics and horsemanship. Among those in his class were Oliver O. Howard, Stephen D. Lee, William D. Pender, and Stephen H. Weed. While at West Point, Stuart first came in contact with Colonel Robert E. Lee who was appointed superintendent of the academy in 1852. During Stuarts time at the academy, he achieved the cadet rank of second captain of the corps and received the special recognition of cavalry officer for his skills on horseback. Early Career Graduating in 1854, Stuart placed 13th in a class of 46. Commissioned a brevet second lieutenant, he was assigned to the 1st US Mounted Rifles at Fort Davis, TX. Arriving in early 1855, he led patrols on the roads between San Antonio and El Paso. A short time later, Stuart received a transfer to the 1st US Cavalry Regiment at Fort Leavenworth. Acting as the regimental quartermaster, he served under Colonel Edwin V. Sumner. During his time at Fort Leavenworth, Stuart met Flora Cooke, daughter of Lieutenant Colonel Philip St. George Cooke of the 2nd US Dragoon. An accomplished rider, Flora accepted his marriage proposal less than two months after they first met. The couple were married on November 14, 1855. For the next several years, Stuart served on the frontier taking part in operations against the Native Americans and working to control the violence of the Bleeding Kansas crisis. John Brown. Photograph Courtesy of the Library of Congress On July 27, 1857, he was wounded near the Solomon River in a battle with the Cheyenne. Though struck in the chest, the bullet did little meaningful damage. An enterprising officer, Stuart invented a new type of saber hook in 1859 which was accepted for use by the US Army. Issued a patent for the device, he also earned $5,000 from licensing the design the military. While in Washington finalizing the contracts, Stuart volunteered to serve as Lees aide in capturing radical abolitionist John Brown who had attacked the armory at Harpers Ferry, VA. Fast Facts: Major General J.E.B. Stuart Rank: Major GeneralService: US Army, Confederate ArmyBorn: February 6, 1833 in Patrick County, VADied: May 12, 1864 in Richmond, VANickname: Knight of the Golden SpursParents: Archibald and Elizabeth StuartSpouse: Flora CookeConflicts: Civil WarKnown For: First Battle of Bull Run, Peninsula Campaign, Second Battle of Manassas, Battle of Antietam, Battle of Fredericksburg, Battle of Chancellorsville, Battle of Brandy Station, Battle of Gettysburg, Battle of the Wilderness, Spotsylvania Court House, Battle of Yellow Tavern Road to War Finding Brown holed up at Harpers Ferry, Stuart played a key role in the attack by delivering Lees surrender request and signaling the assault to begin. Returning to his post, Stuart was promoted to captain on April 22, 1861. This proved short-lived as following Virginias secession from the Union at the beginning of the Civil War he resigned his commission to join the Confederate Army. During this period, he was disappointed to learn that his father-in-law, a Virginian by birth, had elected to remain with the Union. Returning home, he was commissioned a lieutenant colonel of Virginia Infantry on May 10. When Flora gave birth to a son in June, Stuart refused to allow the child to be named for his father-in-law. The Civil War Assigned to Colonel Thomas J. Jacksons Army of the Shenandoah, Stuart was given command of the organizations cavalry companies. These were quickly consolidated into the 1st Virginia Cavalry with Stuart in command as colonel. On July 21, he took part in the First Battle of Bull Run where his men aided in the pursuit of the fleeing Federals. After service on the upper Potomac, he was given command of a cavalry brigade in what would become the Army of Northern Virginia. With this came a promotion to brigadier general on September 21. Lieutenant General Thomas Stonewall Jackson. Photograph Courtesy of the National Archives Records Administration Rise to Fame Taking part in the Peninsula Campaign in the spring of 1862, Stuarts cavalry saw little action due to the nature of the terrain, though he did see action at the Battle of Williamsburg on May 5. With the elevation of Lee to command at the end of the month, Stuarts role increased. Dispatched by Lee to scout the Union right, Stuarts brigade successfully rode around the entire Union army between June 12 and 15. Already known for his plumed hat and flamboyant style, the exploit made him famous across the Confederacy and greatly embarrassed Cooke who was commanding the Union cavalry. Promoted to major general on July 25, Stuarts command was enlarged to the Cavalry Division. Taking part in the Northern Virginia Campaign, he was nearly captured in August, but later succeeded in attacking Major General John Popes headquarters. For the remainder of the campaign, his men provided screening forces and flank protection, while seeing action at Second Manassas and Chantilly. As Lee invaded Maryland that September, Stuart was tasked with screening the army. He failed somewhat in this task in that his men failed to gather key intelligence regarding the advancing Union army. The campaign culminated on September 17, at the Battle of Antietam. His horse artillery bombarded Union troops during the opening phases of the fight, but he was unable to conduct a flank attack requested by Jackson that afternoon due to heavy resistance. In the wake of the battle, Stuart again rode around the Union army, but to little military effect. After providing routine cavalry operations in the fall, Stuarts cavalry guarded the Confederate right during the Battle of Fredericksburg on December 13. During the winter, Stuart raided as far north as Fairfax Court House. Chancellorsville Brandy Station With the resumption of campaigning in 1863, Stuart accompanied Jackson during the latters famed flanking march at the Battle of Chancellorsville. When Jackson and Major General A.P. Hill were severely wounded, Stuart was placed in command of their corps for the remainder of the battle. After performing well in this role, he was badly embarrassed when his cavalry was surprised by their Union counterparts at the Battle of Brandy Station on June 9. In a daylong fight, his troopers narrowly avoided defeat. Later that month, Lee began another march north with the goal of invading Pennsylvania. Gettysburg Campaign For the advance, Stuart was tasked with covering the mountain passes as well as screening Lieutenant General Richard Ewells Second Corps. Instead of taking a direct route along the Blue Ridge, Stuart, perhaps with the goal of erasing the stain of Brandy Station, took the bulk of his force between the Union army and Washington with an eye to capturing supplies and creating chaos. Advancing, he was driven further east by Union forces, delaying his march and forcing him away from Ewell. While he captured a large amount of supplies and fought several minor battles, his absence deprived Lee of his prime scouting force in the days prior to the Battle of Gettysburg. Arriving at Gettysburg on July 2, he was rebuked by Lee for his actions. The next day he was ordered to attack the Union rear in conjunction with Picketts Charge but was blocked by Union forces east of the town. Though he performed well in covering the armys retreat after the battle, he was later made one of the scapegoats for the Confederate defeat. That September, Lee reorganized his mounted forces into a Cavalry Corps with Stuart in command. Unlike his other corps commanders, Stuart was not promoted to lieutenant general. That fall saw him perform well during the Bristoe Campaign. Final Campaign With the beginning of the Union Overland Campaign in May 1864, Stuarts men saw heavy action during the Battle of the Wilderness. With the conclusion of fighting, they shifted south and fought a vital action at Laurel Hill, delaying Union forces from reaching Spotsylvania Court House. As fighting raged around Spotsylvania Court House, the commander of the Union cavalry, Major General Philip Sheridan, received permission to mount a large raid south. Driving across the North Anna River, he was soon pursued by Stuart. The two forces clashed at the Battle of Yellow Tavern on May 11. In the fighting, Stuart was mortally wounded when a bullet struck him in the left side. In great pain, he was taken to Richmond where he died the next day. Only 31-years old, Stuart was buried at Hollywood Cemetery in Richmond.

History Essay Example | Topics and Well Written Essays - 500 words - 5

History - Essay Example When industrialization came, machines replaced small weavers, farmers left their lands because of obtrusive laws, and many families had to work at factories and had to live in the cities. Life in the cities meant higher living expenses, working longer hours and extremely stretching of expenses. Wife and children had to work for eighteen hours and the only time family came together was to sleep. They had no choice but to live together in one housing unit with other families to save on costs. Thus life of family at the start of industrial revolution was unbearable because working families often lived in slum areas with unsanitary conditions. Children received little education, often sickly, and suffered stunted growth. Mortality rate was great with 50% of children dying before reaching age two. Another significant consequence was inequality in groups because women and children were paid less and were required to work more hours. Factory owners were happy to employ children because they could manipulate children easier than adults, often thru beatings. Children as young as eight years old were sent to textile manufacturing, coals and mines. Workers during this time were locked up in a system where they had no control. B. Discuss the relationship between the Industrial Revolution and the development of capitalism.

Critical analysis of ralph ellison's discrimination Research Paper

Critical analysis of ralph ellison's discrimination - Research Paper Example learns that the government and society promote and condone racism, and that racism stifles the ability of black people to reach their full potential as human beings. The government creates laws and institutions that promote institutional racism. Schools should be a place for equal learning, but Ellison reveals its true purpose: â€Å"[it was a] new public school †¦exclusively for whites† (Ellison page 66 par. 1). Blacks and whites are equally paying their taxes, but the public systems prefer to serve the whites. Clearly, the education is geared toward the education of the dominant race and aims to leave the poor minorities in a deep level of ignorance. Furthermore, Ellison’s daily experiences toward his school reflect the disparaging gap, not only between the rich and the poor, but between whites and blacks. He talks about the route of a â€Å"viaduct,† warehouses,† and â€Å"docks, even a â€Å"red-light district† on the way to school (Ellison 66.2). This kind of route is not appropriate for young students, but apparently, the blacks are located far enough from school and near their workplaces. The settin g indicates social segregation, where the whites have placed the blacks in their proper place. In addition, the government controls public entertainment spaces. Ellison wants to go to the zoo, but it is suddenly closed to black children. He wants to understand the reason why he cannot see the zoo, while white children can, but her mother says: â€Å"Quit asking questions, it’s the law†¦Ã¢â‚¬  (Ellison 66.4). The idea of no longer questioning the law indicates the political powerlessness of the blacks. When public spaces are white spaces, the government further entrenches the blacks in poverty and powerlessness. Society condones racism because of its inability to integrate the whites and the minorities as equals. The red-light district symbolizes the peripheral and subordinate treatment of blacks. The black prostitutes feed the white men’s desire, which reflects

Mona Lisa Assignment Example | Topics and Well Written Essays - 250 words

Mona Lisa - Assignment Example I find the facial expression of Mona Lisa somewhat vague and enigmatic as if there is some mystery behind her half smile. Her calm pose suggests the same. Her eyes and hair too have an innate power to attract the viewer. This is one of the special features of the painting because it is remarkable how Leonardo managed to capture such an emotional state within a portrait. It is not so much the attention to detail such as the folds on her sleeves for example, but capturing this mysterious expression and use of the sfumato (gentle toning down) (Queiros-Conde 2004) technique overall that demonstrates his true greatness as a painter. Others have described the painting in a similar way too but I do not believe it is hype. If the story about trying to amuse Mona before making her portrait (Vasari 2006) is true this shows in her expression but I still believe there is more hidden beneath the surface. Perhaps there is some truth concerning the recent nude Mona Lisa discovery (Lorenzi 2009). It s parallels with the original Mona Lisa could indicate that the painter and the painted had a special rapport and liking for each other. If so, this explains much of the natural yet mysterious expressions of the Mona Lisa. The Mona Lisa is a good example of the High Renaissance style because like the paintings of Raphael and Michelangelo, it is a portraiture and work of beauty showing an â€Å"artist’s individual skills and vision† (pbs.org). This was the typical style of painting at the time besides art for historical and religious purposes. â€Å"The idea that painters and sculptors might create from personal inspiration was new† (ibid) during the Renaissance period. But what makes the painting characteristically a work of Leonardo da Vinci are the painstaking effort that must have gone into it, the skilful use of the sfumato, the careful portrayal of perspective, and the strong sense of imagination coupled with

Gene-ablation and other genetic technique

Gene-ablation and other genetic technique How has the use of gene-ablation and other genetic techniques in mice altered our approach to scientific problems in pharmacology and physiology? 280 pts (8-12 pages, 11pt Arial font, double spaced) A gene is a region of DNA that controls a discrete hereditary characteristic, usually corresponding to a single protein or RNA1. Most scientists are interested in determining how genes, and the proteins they encode, function in the intact organism. One of the most direct ways to find out what a gene does is to see what happens to the organism when that gene is missing. Because mutations can interrupt cellular processes, mutants often hold the key to understanding gene function. A well accepted strategy for evaluating gene function is to create and characterize a gene knockout mouse. Virtually any gene in the germ line can be mutated through gene targeting in totipotent embryonic stem (ES) cells or to use gene ablation technology to knock-out either a specific gene or a specific cell type in an intact animal2. Both of these methods offer almost unlimited possibilities for addressing questions concerning the molecular and cellular biology of development, the relationship between geneti cs and biological function, unraveling the causes of disease, and enhance pharmaceutical research. ES cells are a versatile source of cells for repair of damaged and defective tissues in the adult body2. Totipotent embryonic stem cells have been used in vitro to generated precursors for oligodendrocytes and astrocytes. Transplantation of these ES cells into a model mouse of human myelin disease allowed the precursors to interact with host neurons and efficiently myelinate axons in brain and spinal cord. Further investigation of this mechanism could lead to pharmacological, physiological and therapeutic treatments. ES cells also make possible the most precisely controlled forms of genetic modification, allowing animals to be created with virtually any desired alteration introduced into their genome2. One way to produce a transgenic (knockout) animal is through gene targeting in totipotent ES cells. By incorporating a null allele into one allele of murine ES cells, and injecting these cells into early mouse embryos, one can create chimeric mice (heterozygous for the knockout allele) containing tissues derived from both host cells and ES cells2. Mating the chimeric mice allows one to confirm that the null allele is incorporated into the germ line and can breed these heterozygous chimeric mice to homogeneity producing progeny that are homozygous knockout mice2. A knockout mouse generated to carry a mutating apolipoprotein E (apoE) gene through inactivation by gene targeting in embryonic stem cells can be used as a model for atherosclerosis. apoE is a constituent of very low density lipoprotein (VLDL) synthesized by the liver and of a subclass of high density lipoproteins (HDLs) involved in cholesterol transport among cells. In humans a variant form of apoE, has been found to be defective in binding to the LDL receptor that is associated with familial type III hyperlipoproteinemia, a disease characterized by elevated plasma cholesterol and premature coronary heart disease. apoE deficient mice develop severe hypercholesterolemia due to a delayed clearance of large atherogenic particles from the circulation. A study was done to analyze the genesis of atherosclerotic lesions, including the nature of the cells involved, the sequence of cellular events and the anatomic location of specific lesion types over time on mice fed a normal or a high fat diet. They found that the lesions were distributed thought the arterial tree and contained many features of the specialized, chronic, inflammatory-fibroproliferative response characteristic of atherosclerosis with age. This mouse model is used to better understand the physiological role of apoE in lipid metabolism, atherogenesis, and nerve injury. The model can also be used as a way to test new pharmacological drugs in pre-clinical trials to determine drug interaction, new therapeutics or to develop variations of current drugs to better meet the needs of the vast array of genetic variability seen in the human population today. Gene ablation involves the homologous genetic recombination of a gene in such a way that the gene has been made â€Å"null†. Genetic ablation is a genetic engineering technique used to suppress selectively the growth of a specified cell line or cell type in an animal rather than suppress the activity of an individual gene2. Analyzing the in vivo function of cells can be accomplished through specific cell ablation. Using genetic ablation to produce a knockout mouse involves the injection of one or more transgenes (usually a DNA segment bearing its own promoter) into the pronucleus of a fertilized mouse oocyte, which, after reimplantation into a foster mother, gives birth to a transgenic mouse bearing one of several hundred copies of the transgene3. These mice again can be bred to produce a homozygous colony. An overexpression Sod2 transgenic mouse was generated through the use of pronuclear injection of the Sod2 gene into fertilized eggs. These mice overexpressed superoxide dismutase which catalyzes the conversion of superoxide anion to hydrogen peroxide and oxygen. Superoxide anions are reactive oxygen species (ROS) generated in the respiratory chain as a byproduct of mitochondrial respiration. ROS cause oxidative damage to key mitochondrial components, such as protein, lipids and DNA. They are thought to lead to an overall decline in cellular function and ultimately determine the life span of an organism. Sod2 trangsenic mice have been used to test the effects of overexpressing MnSOD on mitochondrial function, levels of oxidative stress or damage and live span in mice. They found that a two fold increase of MnSOD throughout the life of the organism resulted in a slight decrease in oxidative damage and enhanced resistance against oxidative stress. Oxidative damage is also associated wit h arthritis, heart disease, gastrointestinal disorders, multiple sclerosis, cancer and neurological diseases. This model can be used to physiologically improve ones understanding of oxidative stress and to develop pharmaceutical agents that can enhance ones ability to decrease or protect against oxidative damage. Customized gene targeted animal models include constitutive knockouts or knock-ins, or conditional knockouts or knock-ins of known genes, a gene family, mutant genes or artificially created reporters and gene constructs. A constitutive knockout is a model that provides a broad overview of gene function, by the inactivation of the gene of interest at the genetic level, by random mutation or targeted insertion4. The advantage of using this model is that you get a total inactivation of the gene in any cell4. The disadvantage of this model is that the phenotypes can be complex since all organs are affected4. A conditional knockout is a model that provides a research model of high potential, by targeting tissue-specific inactivation of the gene of interest, through the use of recombinase4. Recombinase is an enzyme that deletes the DNA fragment located between the two recombinase-specific sites4. This tissue-specific expression of the recombinase allows the inactivation of the gene of inte rest only in the tissue were the recombinase is expressed4. There are two advantages to using this model, the first is the inactivation is restricted to specific tissues and the second is that several tissue-specific models can be made in parallel4. The disadvantages of using this model include the efficiency of the excision and the inability to validate the recombinase system4. There are a number of other strategies that can be used in place of, or to complement, conventional gene knockout technology. Two such examples are regulatable gene ablation and temporary gene ablation (gene knock downs). Ablation of a gene can be spatially or temporally regulated, that is only the organ of interest is affected or the mutation occurs only in one particular developmental state5. Through the use of a regulator, the promoter can be regulated to control gene expression in the organ or particular tissue of interest. A gene knockdown refers to the technique by which the expression of one or more of an organisms genes is reduced, either through genetic modification or by treatment with a reagent such as a short DNA or RNA oligonucleotide with a sequence complementary to either an mRNA transcript or a gene6. These approaches offer a rapid and economical method to examine the specific actions of a gene product at a particular time point. Genes can be transiently down-regulate d by targeted blockade of gene expression, either systemically or within a specific tissue. Two such approaches are antisense technology and the use of short interfering RNA (siRNA). Antisense technology is the use of short modified DNA sequences complementary to the mRNA of the gene of interest2. These sequences bind to the 5UTR and the beginning of the coding sequence therefore preventing translation initiation and blocking ribosomal interaction with the AUG start codon2. Antisense oligonucleotide genetic-code blocking drugs might control disease by inhibiting deleterious or malfunctioning genes. siRNA on the other hand, utilizes small lengths of double stranded RNA designed against the gene of interest and is introduced into the cell where they interact with intracellular machinery to form RNA-induced silencing complexes (RISCs)2. These complexes unwind the siRNA strands and allow specific binding to the complementary mRNA sequence2. This binding causes cleavage and destruction o f the now double stranded mRNA, and subsequently prevents translation2. siRNA can be used to study gene function, manipulating gene expression, as well as drug development. siRNA compounds can be created and delivered into human cells were they are able to silence genes and viruses responsible for human diseases. Two other genetic techniques that are used to approach gene investigation include suppressor analysis and reverse genetics. Suppressor analysis is used to identify genes that are functionally related to another gene of interest7. A suppressor mutation is a mutation that counteracts the effects of another mutation thereby reducing its phenotypic effect7. Suppressor mutations may be intragenic (in the same gene as the original mutation) or intergenic (in another gene)7. Intergenic suppressor mutations can be either information suppressors or function suppressors7. Of the two, function suppressors are most valuable for the genetic analysis of cellular processes7. Reverse genetics is a process in which specific mutations are introduced into a cloned gene for the purpose of identifying functional domains8. One way to conduct reverse genetics is to do RNA interference (RNAi)8. RNA interference is an in vivo gene knock-down, which is used to insert a random shRNA construct into the mouse ge nome4. Here, double-stranded RNAs inhibit corresponding gene expression by inducing degradation of its mRNA4. RNAi can be used as part of the immune response to viruses and other genetic material; it can also be used to look at downregulation and upregulation of genes4. RNAi has been used to evaluate whether insulin-like growth factor binding protein-3 (IGFBP3) modulates gastrointestinal stromal tumor (GIST) cell response. Here, transfection of siRNA to knockdown IGFBP3 gene into GIST cells resulted in a significant loss of cell viability and therefore found that IGFP3 gene is required for GIST cell survival. IGFBP3 gene expression is lost in many cancer cells and reintroduction of the protein often results in cell death. On the other hand IGFBP3 has been linked to renal cell carcinoma, breast cancer, and metastatic melanoma, which suggests that IGFBP3 may contribute to tumorigenesis or disease progression. By studying IGFBP3 and the IGF pathway one can explore IGF for prognostic an d therapeutic value in GISTs and other cancers. In order to develop new treatment and preventative strategies for a human disease, we must first understand the biology and pathogenesis of the human disease itself10. A way to study human gene function is by mouse gene humanization. Humanization is the replacement of the murine gene by its human counter part4. Animal models of human disease have been crucial in elucidating normal organ biology, pathogenic mechanisms of the disease and developing new therapeutic strategies10. Animal models are being used instead of human studies, because human studies are limited by a number of factors such as: the variability seen in genetic background and environmental influences, the inability to readily obtain human tissues for molecular analysis and the small numbers of patients who may have a particular genetic abnormality10. Transgenic animals have already made valuable research contributions to studies involving regulation of gene expression, the function of the immune system, genetic diseases, viral diseases, cardiovascular disease, and the genes responsible for the development of cancer. Transgenic animal models are most effective if they have both construct validity and face validity. Construct validity is the degree to which the model corresponds to the clinical state in humans. Face validity is the animal model responds in an appropriate manner to the effects of different therapeutic agents. An animal model that can recapitulate at least part of the neuropathology and the cognitive and behavioral impairment is the most effective representative of the disease. Several rodent models of Alzheimers disease (AD) have been created. The first example of such a model has been created to mimic the cholinergic deficits of AD patients and to investigate the role of the central cholinergic system in the cognit ive and behavioral deficits observed in AD9. The second example of such a model has been created with acute or chronic injections of amyloid beta within the brain parenchyma of rodents, to overexpress AD-related mutated protein (amyloid deposits) in the central nervous system of rodents9. A third model of AD has been to create a transgenic mouse to express wild-type or mutant forms of the human APP and/or PS genes. All three of these models provide many insights into AD pathogenesis and approached to new therapies. By exploring and understanding of the neuropathological processes underlying the cognitive deterioration leading to dementia and investigating of the effects of potential new treatments on both AD neuropathology and cognitive deficits we will be able to test drugs that could potentially alleviate symptoms of the disease. Transgenic animals have also been used to develop animal strains that secrete important proteins in milk2. These animals are used to synthesize recoverable quantities of therapeutically useful proteins. These proteins can be harvested from the animal by simply milking the animal and then using separation techniques for protein purification2. For example cows have been used to purify collagen which can then be used to indicate burns and bone fracture2. Pigs have been used to purify human hemoglobin as a blood replacement for transfusion2. Goats have been used to make monoclonal antibodies for colon cancer2. In addition sheep have been used to make factor VIII and factor IX for hemophilia2. Despite the large amount of knowledge that can be gained by knockout studies, there are some important considerations to be taken when investigating the role of a particular protein or gene of interest. These considerations include but are not limited to: redundancy, lethality, delineating systemic vs. local effects, subtle effects, and specific pathogen free conditions3. Gene redundancy is the existence of multiple copies of the same gene in the genome of an organism. This problem can be overcome to some extent by the use of multiple knockouts or in some situations where multiple ligands bind to the same receptor, a dominant negative receptor approach can knockout the effects of all ligands at once5. Lethality phenotypes severely compromise the ability of the organism to function. Some knockouts are developmentally lethal, which means that the genetically altered embryos cannot grow in adult mice. Knocking out a gene may also fail to produce an observable (phenotypic) change in a mo use or may even produce different characteristics from those observed in humans in which the same gene is inactivated. In some instances, a particular organ of interest can be transplanted into a healthy wild type host in order to conduct the analysis on that organ. Local effect refers to an adverse health effect that takes place at the point or area of contact, for example the respiratory tract11. Systemic effect refers to an adverse health effect that takes place at a location distant from the bodys initial point of contact and assumes absorption has taken place, i.e. absorption into the blood stream11. Subtle effects are those that are so slight as to be difficult to detect or describe. For example, small changes in nutrient delivery to the fetus can program post-natal and adult metabolic status and lead to increased susceptibility to a range of adult onset disease, including stroke, hypertension and non-insulin dependent diabetes5. Specific pathogen free conditions refers to the fact that laboratory mice in research institution are generally housed in a specific pathogen free environment, and are therefore not challenged with the array of pathogens most mice and humans are exposed to. When comparing transgenic models to humans a key difference could be in the initiation of the development or process in the mouse that may not have a similar mechanism as the human development or process it is thought to represent. The presence of a specific mutation in the mouse from the time of its conception may enable a distinction between phenotypic changes due to the mutation itself and changes caused by adaptation and compensation for the mutation12. A gene can also be expressed in different tissues where it may have different functions; its alteration may induce unexpected consequences. Also, the function of two genes may overlap or a mutation in a single gene might not reveal an abnormal phenotype. There is also a possibility of random incorporation into genome, which may inadvertently disrupt other genes, or have a variable degree of gene silencing success. The gene may also induce gross morphologic or physiologic abnormalities that affect the gene directly. Note also, thes e animal models also only play a minor role in drug development, as relatively few human diseases are monogenetic12. In most cases, gene ablation and other genetic techniques must address the basic question as to whether a particular gene, wild type, or mutant is involved in the pathogenesis of a particular disease. If not a particular disease, it may also address whether a gene product which plays a role in a specific signaling process contributes to disease in conjunction with other predisposing conditions. Animal models are crucial in providing a unified understanding of how drugs work, developing new therapeutic agents, and obtaining critical data needed to advance compounds into clinical trails12. Animal models are an important tool for scientist to investigate human diseases, especially in order to conduct time-course studies or when studying early disease. Transgenic and knockout animals are also used to determine the molecular mode of action of a gene product and the downstream consequences of its misexpression on normal processes. Assessing the role of a specific gene can know be accomplis hed through the use of transgenic animals whose genomes have been manipulated to under- or overexpress a target gene, or express it in a modified or defective, nonfunctional form12. Animal models represent an attempt to imitate the pathologies associated with human disease states in a preclinical setting12. References: Molecular Biology of the Cell. Alberts, et. al. 4th edition 2002 Garland Science New York, NY. Crommelin, D.J.A. and Sindelar, R.D. (1997). Pharmaceutical Biotechnology: Fundamentals and Applications, Third Ed. Taylor and Francis. Philadelphia, PA. Seidman, J.G. (2009) Manipulating the Mouse Genome. Current Protocols in Molecular Biology. January 01. Reliable and Innovative Solutions for Transgenesis. Accessed on 11/4/2009. Ingman, WV. And Jones, RL. (2008). Cytokine knockouts in reporduciton: the use of gene ablation to dissect roles of cytokines in reproductive biology. Human Reproductive Update 14(2): 179-192. Gene knockdown. (2009, June 8). In Wikipedia, The Free Encyclopedia. Retrieved 13:53, November 8, 2009, from Fay, D. and Johnson, W. (2006). Genetic mapping and manipulation: Chapter 10-Suppressor mutations. Accessed on 11/5/2009. Bio-Medicine. Accessed on 11/4/2009. Dodart, J.C. and May P. (2005) Overview on Rodent models of Alzheimers Disease. Current Protocols in Neuroscience. November 01. Lind J. and Semsarian C. (2006) Overview of Model Systems for the Analysis of Human Disease. Current Protocols in Human Genetics. February 01. Local vs. Systemic Health Effects. Accessed on 11/3/2009. Moser, P. (2009) Animal Models of Disease. Current Protocols in Pharmacology. September 01. Katz, D.A. (2007) Overview of Pharmacogenetics. Current Protocols in Pharmacology. March 01. Barash, CI. (2001)Ethical Issues in Pharmacogenetics. Accessed on 11/4/2009. Frequently Asked Questions about Pharmacogenetics. Accessed on 11/4/2009. Bustle, O., Jones, K.N., Learish R. D., et.al.(1999) Embryonic Stem Cell-Derived Glial Precursors: A source of Myelinating Transplants. Science 5428(285): 754-756 Piedrahita, J.A., Zhang, S.H, Hagaman, J.R, Oliver, P.M, and Maeda N. (1992) Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc. Natl. Acad. Sci. USA. 89:4471-4475. Nakashima, Y, Plump AS, Raines E.W, Reslow J.L, and Ross R. (1994) ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arteriosclerosis and Thrombosis 14:133-140. Jang Y.C et.al (2009). Overexpression of Mn Superoxide Dismutase Does Not Increase Life Span in Mice. Journal of Gerontology:Biological Sciences. 64(11): 1114-1125. Dupart JJ. Et.al (2009). Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro. Mol Cancer Nov 10;8(1):99 (Epub ahead of print) PMID: 19903356 Genes associate with drug responses can be grouped into three broad categories: those involved in pharmacokinetics (i.e. drug metabolism, transport), those encoding pharmacological targets (i.e. drug-target pathways) and those with physiological associations (i.e. homeostasis pathways)13. Pharmacokinetic pathways mediate drug absorption, distribution, metabolism and excretion13. Pharmacological pathways such as transcription factors and phosphorylation targets whose genes encode other proteins are also candidates for pharmacogenetic analysis13. Understanding the sensitivity of a particular drug and the genes that encode the drug metabolizing enzymes can help determine how the particular drug is transported and metabolized within the body. Understanding the gene variants and how they influence drug concentrations at the target site is a possible way to explain the differences in response to a particular drug dose among individuals. Pharmacogenetics is the study of how an individuals genetic differences influence drug action, usage and dosing2. The molecular compositions of enzymes are currently being identified through the use of the Human Genome Project. Scientists are able to study these enzymes and determine correlations between genotypic and phenotypic variability14. These current advances will allow scientists to use the molecular knowledge of enzymes to detect individuals who are likely to experience adverse reactions to medicines without having to use potentially dangerous methods of trial and error14. An offshoot of pharmacogenetics is pharmacogenomics, which attempts to understand not only the molecular composition of genetic variants associated with drug response but also the behavior of those variants14. Pharmacogenomic knowledge can be used to spot the disease before it occurs in a patient, increase drug efficacy upon pharmacotherapy, and reduce drug toxicity2. It could also facilitate the drug development process to improve clinical development outcomes, reducing overall cost of drug development and lead to development of new diagnostic tests that impact on therapeutic decisions2. Pharmacogenomics can be used by doctors to identify the optimal dose and medicine for each individual patient with greater efficacy and safety. As the dosage would be based on factors such as age, weight, diet, lifestyle, liver and kidney function. By using a pharmacogenetic test a doctor can determine the right dose for individual patients. There are phomacogenetic tests for cancer, HIV, depressio n, and cardiovascular disease15. These tests take in the factors which are most likely to affect the absorption and effectiveness of the drug. There are many benefits that can come from pharmacogenetics and pharmacogenomics. Pharmaceutical companies can use information obtained to create more powerful medicines based on proteins, enzymes, and RNA molecules associated with genes and diseases15. Again, doctors would be able to analyze a patients genetic profile and prescribe the best available drug therapy from the beginning instead of the standard trial and error method of matching patient with the right drugs. A more appropriate drug dosage could be determined by not only taking in a persons weight and age but also accounting for their individual body processes, such as the time it takes for their body to metabolize the drug. Pharmacogenetics could also provide advance screening for disease, better vaccines, improvements in the drug discovery and approval process and decrease the overall cost of health care15. Pharmacogenomics is still in the development stage in the research field. There are several factors that need to be overcome before many of the pharmacogenomic benefits can be realized. These include the complexity of finding gene variations that affect drug response, the limitation of current drug alternatives, disincentives for drug companies to make multiple pharmacogenomic products, and educating health care providers14. There are also ethical issues to consider, such as lack of data privacy, possibility that adverse reactions to drugs can occur during treatment, the cost of such designer drugs will be to expensive for everyone, and genetic testing can provide an array of diagnostic results (predisposal test) which may or may not be what the patient wants to know14.

The Possibilities of the Gap Year Essay -- The Gap Year Abroad

A gap year is a year off of academics, which provides time to explore interests and help determine career choices, containing both positive and negative aspects to consider. A gap year can be spent in a several ways from internships, working, volunteering, or traveling and exploring interests. It can provide students with life impacting traits that can provide a better future and greater outlook on life. If taken seriously, a gap year can have many positive effects on education and the motivation to continue school. Although gap years can be very expensive, it can overall be an opportunity of a lifetime, to create clear academic goals. Although a gap year is most often taken between high school and college, some students decide to take one after under-graduate school and before graduate school or entering the workforce. If a gap year is planned properly, it can help a students take school and life more seriously impacting their entire life. In the UK and similarly in Australia, 11% of university bound students take a gap year (MacDonald 1). Meaning, that almost one in ten students, in the UK and Australia, whom already were planning on attending a university, take part in a gap year. One reason gap years have become popular is that parents have noticed that students are going to college because it is expected of them or for the social aspect, not because they have clear education or career goals in mind (Bull 77). This causes some parents to rethink the idea of a gap year, because college tuition is increasing every year and they do not want to send their child to school if they are not going for the right reasons. Most ‘gappers’ choose to take a gap year because they want adventure, independence, or they want something more that... ...ons of College and Experiences of Stress Prior to and Through the College Career.† College Student Journal 47.4 (2013): 635-643. OmniFile. Web. 19 March 2014. MacDonald, G. Jeffery. â€Å"Gap Year ‘Before College Gives Grads Valuable Life Experiences.‘† USA Today 18 June 2008: 1-3. USAToday.com. Web. 14 March 2014. O’Shea, Joseph. â€Å"Delaying the Academy: A Gap Year Education.† Teaching in Higher Education 16.5 (2011). 565-577. Web. 16 March 2014. Sarouhan, Jane and Sarouhan, Jason. â€Å"Your Goals, Your Life, Your Gap Year.† CollegeXPress Magazine (2013): 22-25. OmniFile. Web. 14 March 2014. Sutherland, Paige. â€Å"College Offers to Pay Students to Take Time Off.† APFinancial News (2014): 1-2. Newswires. Web. 14 March 2014. Torpey, Elka Maria. â€Å"Gap year: Time Off with A Plan.† Occupational Outlook Quarterly 53.3 (2009): 26-31. Business Source Complete. Web. 14 March 2014.